Free Flow Flava Final Round Extended
While Tonedeff kept the fan base satiated with consistent releases, everything was leading up to his studio album, which was delayed a few times. On April 5, 2005, Tonedeff released his first official full-length album, Archetype. The long-awaited album was met with acclaim from fans and reviewers alike. HipHop DX gave Archetype an 8/10, praising Tonedeff's versatility and calling him "among the finest this genre has to offer." In a review for IGN, Jim During seconded those sentiments, concluding "With one of the best flows in hip hop, Tondeff puts out a well-rounded debut." In support of Archetype, Tonedeff embarked on international tours for the next years, including the QN5 Spring Cleaning National Tour and a Scandinavian tour in 2006, and performing at Rock The Bells among many other festivals.
Free Flow Flava Final Round Extended
Tonedeff received more national recognition when selected to perform at the August 2006 Lollapalooza festival in Chicago. He earned his nomination by garnering some of the highest vote totals throughout the "Last Band Standing" competition and finally selected as the winner after four rounds of celebrity-panel judging (which included Lollapalooza founder Perry Farrell of Jane's Addiction) and a live-performance round. Other performers at the event were Common, Kanye West, and Gnarls Barkley.
Epidural SpaceThe epidural space surrounds the dura mater circumferentially and extends from the foramen magnum to the sacrococcygeal ligament. The space is bound posteriorly by the ligamentum flavum, laterally by the pedicles and the intervertebral foramina, and anteriorly by the posterior longitudinal ligament. Of the three epidural space compartments (posterior, lateral, and anterior), the posterior epidural space is most relevant clinically. The epidural space in general contains adipose tissue, blood vessels, nerve roots, and loose connective tissue in a nonuniform distribution. The veins in the space are continuous with the iliac vessels in the pelvis and the azygos system in the abdominal and thoracic body walls. Because the plexus is valveless, blood from any of the connected systems can flow into the epidural vessels.
Side effects that are commonly associated with epidural clonidine include dose-independent hypotension, bradycardia, sedation, and dry mouth. Combining clonidine with other agents, such as opioids, anticholinergics, opioid agonist-antagonists, and ketamine, may enhance the beneficial effects of these drugs while minimizing adverse side effects.Neostigmine, a cholinesterase inhibitor, is a more recent addition to the list of epidural additives for selective analgesia. The mechanism of action for its analgesic effect appears to be the inhibition of the breakdown of acetylcholine and the indirect stimulation of muscarinic and nicotinic receptors in the spinal cord. Although experience with epidural neostigmine is limited, it has been reported to provide postoperative pain relief without inducing respiratory depression, motor impairment, or hypotension. When combined with other opioids, clonidine, and LAs, it may provide benefits similar to clonidine without the side-effect profile of any of these drugs given alone. Observations in patients with cancer pain showed promise that its use might be associated with less nausea and vomiting than the intrathecal application. In an investigation randomizing 48 patients to receive 0, 1, 2, or 4 μg/kg of epidural neostigmine in addition to a bupivacaine spinal anesthetic for minor knee surgery, no case of intraoperative nausea or vomiting was observed, and postoperative nausea scores did not differ between groups. These results need to be corroborated by further studies before epidural neostigmine can be recommended for daily practice.Other agents, such as ketamine, tramadol, droperidol, and midazolam, have been considered for epidural administration, with mixed results. Considerable controversy surrounds the use of midazolam intrathecally. Despite multiple publications recommending its use, recent studies have demonstrated that even a single dose of intrathecal midazolam may have neurotoxic effects. Until its safety profile can be ensured in human subjects, it is not recommended for neuraxial use at this time.One agent that shows promise is the extended-release formulation of one of the oldest opioids, morphine. DepoDur, the brand name for extended-release epidural morphine, uses a drug-release delivery system called DepoFoam. DepoFoam is composed of microscopic lipid-based particles with internal vesicles that contain the active drug and slowly release it. Recent studies have demonstrated effective pain relief with relatively minor side effects for up to 48 hours when appropriately dosed. However, concerns about delayed respiratory depression have limited its clinical use in this early stage of its clinical use.
An extremely vigorous twining vine growing to 25-30 feet with large rounded, dark green leaves. Because of its size it will need a substantial support. Will grow in full sun to shade. Flowering in May-June, the unique flowers are greenish-yellow and shaped like a meerschaum pipe. Unfortunately, the flowers often go overlooked as they are buried under the large foliage canopy. Makes a good screen. Prune in late winter to control growth. Prefers a moist soil location.
A rapid, vigorous growing vine climbing by both aerial roots and twining. Grows to 30-40 feet. Will grow in sun to light shade with best flowering in full sun. Because of its vigor this vine will need a substantial support. Large compound green leaves that look almost tropical. Flowers are orange-scarlet, 3 inches long, tube-shaped and showy from July-September. Attractive to hummingbirds and butterflies. After flowering, long, bean-shaped pods are produced that often persist through the winter. Trumpet vine may not flower for several years after planting until it becomes well established in the garden. Looks best when given moisture during dry periods in the garden. Trumpet vine will sucker freely in the garden so use caution about its use in small space gardens. Suckering can be "controlled" by timely removal of suckers by digging as they appear. Also tends to reseed so pull out seedlings as they appear. Vine tolerates heavy pruning in late winter or early spring. This is suggested in order to keep it under control and maintain quality.
Virginia Creeper is a vigorous vine growing to 50+ feet and attaching by both tendrils and holdfasts. Large five-parted leaves are purple color in the spring, and then change to a dull green during the growing season. It then turns a brilliant red in the fall. The inconspicuous flowers develop into clusters of blue-black pea-sized berries that are often eaten by birds. Virginia creeper is tolerant of drought and grows in full sun to shade locations. This vine can also be used as a groundcover or allowed to trail off of retaining walls. This vine is often mistaken for poison ivy that has three-parted leaves. Heavy pruning in the spring may be needed to keep this aggressive vine in check. 'Engelman' is a cultivar that is less vigorous, has small leaves and good for small spaces. 'Star Showers' is a variegated cultivar.
As a group, honeysuckle vines are vigorous, twining vines growing from 10-20 feet tall. Most all offer fragrant flowers from June-July that are attractive to butterflies and hummingbirds. Many also offer attractive foliage and berries. All benefit from heavy pruning in late winter to keep them from becoming overgrown and tangled and to maintain their foliage and flowering quality. Best in full sun locations but will tolerate shaded sites. It is suggested that Japanese Honeysuckle (Lonicera japonica) not be planted due to its invasive nature. Look for natives or interspecific hybrids as better choices. As a way to tell the Japanese honeysuckle from other honeysuckles look for the following features. With native honeysuckles flowers are borne at the tips of the stems followed by red or orange berries. The leaves are fused or united to form a "collar" around the stem. With Japanese honeysuckle flowers are borne in the leaf axils followed by purple-black berries. The leaves are not fused or united around the stem.
Perennial sweet pea is a vigorous vine growing 9-12 feet tall and attaching by tendrils. It does best in full sun and blooms July-August. It is drought tolerant and provides flowers in the heat of the summer when annual sweet peas fail. Flowers are fragrant and make good cut flowers. Perennial sweet pea will reseed and sucker freely in the garden. Prune very hard in early spring. 041b061a72